Helping me recover from melanoma

My name is Lisa. I am on a journey to recovery and I need your help to meet the cost of dendritic cell therapy in Germany

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Dendritic Cell Therapy Is known as the "Fourth Therapy"

Immunotherapy is currently being researched as the fourth modality for many cancers, after surgery, chemotherapy and radiotherapy. The use of a patient’s own white cells, turned into dendritic cells, is a type of immunotherapy with the potential of boosting host anti-tumour immune responses and dramatically improving clinical outcomes

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FAQs

Dendritic Cell Therapy can be described as a cancer vaccine made from your own blood. In the lab, some of your white cells are, extracted, primed into dendritic cells and trained and multiplied to co-ordinate the presentation of your specific cancer to your immune system.

Dendritic Cell Therapy is not yet available in the UK, privately or through the NHS (National Health Service). There are private clinics in Spain, Germany, Mexico and New York. I chose Germany because of its relatively easy access, the reputation of the clinic and its track record. £35,000 sounds a large sum – and it is a lot of money – but when the fees and costs are broken down, it is relatively modest compared to some other clinics.

The treatment will last from late May 2022 to September/October. The initial treatment took eight days because I had to undertake leukapheresis (extraction of white blood cells) and then wait while my cells were cultured and treated and the remainder stored in a freezer. Six days later, I was vaccinated and then had LDI (low dose immunotherapy). It reduces the likelihood of my immune system reacting against these antigens by exposing the body to extremely diluted antigens, many times less potent than regular doses used in allergy and vaccine therapy. I return for several more vaccinations with my own cells, with LDI, but we won’t know how many until the initial results are investigated.

A great majority of the donations will be spent on clinical fees, medicines, cryostorage of my white cells and treatments. Some will cover other expenses like travel and accommodation, although we will pay for those ourselves where we can. You can see more details of treatment and costs here.

It has not yet been approved by NICE for use in the National Health Service. NICE – the National Institute for Health and Care Excellence – has a role in improving outcomes for people using the NHS and other public health and social care services. There are a few ongoing studies about the efficacy of dendritic cell therapy but not enough evidence for NICE as yet. In Germany, there is more scope for using new therapies at an earlier stage, particularly for life-threatening illnesses Restrictions, protocols and costs have prevented private clinics being set up in the UK.